CALR

Across TCGA patient cohorts, CALR RNA expression is significantly associated with the protein abundance of many other proteins, with 13,698 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CALR-associated proteins across cancer lineages are RCN1, NRDC, and EIF4G1. Each is linked with CALR in more than 5 cancer types. Because this analysis shows association rather than direction, both CALR-to-partner and partner-to-CALR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALR versus RCN1 in PDAC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CALR→partner) and Y-score (partner→CALR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RCN1 →	+0.449	+0.269	<.001	.006	3	6
BRCA	NRDC →	+0.221	+0.389	.002	.001	3	5
CCRCC	EIF4G1 →	+0.254	+0.489	<.001	<.001	3	5
PDAC	SLC16A3 →	+0.723	+0.379	<.001	<.001	3	5
GBM	IGF2R →	+0.387	+0.329	<.001	<.001	3	5
CCRCC	MGAT1 →	+0.319	+0.353	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,698 associations by consensus.

CALR vs RCN1 — PDAC

Explore this scatter interactively →