CALR

Across TCGA patient cohorts, CALR protein abundance is significantly associated with the RNA expression of many other genes, with 20,835 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CALR-associated genes across cancer lineages are GARNL3, MAGI1, and ZNF250. Each is linked with CALR in more than 5 cancer types. Because this analysis shows association rather than direction, both CALR-to-partner and partner-to-CALR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALR versus GARNL3 in LSCC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALR→partner) and Y-score (partner→CALR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GARNL3 →	-0.798	-0.300	<.001	<.001	3	6
GBM	MAGI1 →	-0.753	-0.360	<.001	<.001	3	6
GBM	ZNF250 →	-0.429	-0.387	<.001	<.001	3	6
HNSC	GTF3C4 →	-0.698	-0.225	.007	.004	3	6
BRCA	IDNK →	-0.504	-0.330	<.001	<.001	3	6
BRCA	GAPVD1 →	-0.540	-0.315	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,835 associations by consensus.

CALR vs GARNL3 — LSCC

Explore this scatter interactively →