CALN1

Across TCGA patient cohorts, CALN1 mutation is significantly associated with the RNA expression of many other genes, with 1,341 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CALN1-associated genes across cancer lineages are EIF2S2P7, SBF2-AS1, and HSPE1P22. Each is linked with CALN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CALN1-to-partner and partner-to-CALN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF2S2P7 grouped by CALN1-low versus CALN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALN1→partner) and Y-score (partner→CALN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF2S2P7 →	+0.035	+1.729	.005	.007	3	3
SKCM	SBF2-AS1 →	+0.434	+2.119	.004	.003	3	3
BRCA	HSPE1P22 →	+0.320	+4.398	<.001	.006	3	3
LUSC	NR2C2AP →	+0.558	+3.608	.001	.001	3	3
UCEC	NUDT19P5 →	+0.080	+1.512	.006	.002	3	3
SKCM	RNASEH2A →	+0.506	+2.144	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,341 associations by consensus.

EIF2S2P7 by CALN1 expression — UCEC

Explore this box plot interactively →