CALML5

Across TCGA patient cohorts, CALML5 mutation is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CALML5-associated genes across cancer lineages are LINC01932, RNU6-894P, and RN7SL504P. Each is linked with CALML5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALML5-to-partner and partner-to-CALML5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01932 grouped by CALML5-low versus CALML5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML5→partner) and Y-score (partner→CALML5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01932 →	+0.132	+2.546	.004	.007	3	2
UCEC	RNU6-894P →	+0.395	+4.464	<.001	.005	3	2
SKCM	RN7SL504P →	+0.040	+4.163	<.001	.006	3	2
UCEC	OR6C70 →	+0.055	+3.814	.001	.002	3	1
UCEC	PPP3R2 →	+0.063	+3.448	.001	.001	3	1
UCEC	RNU4-13P →	+0.191	+4.464	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

LINC01932 by CALML5 expression — SKCM

Explore this box plot interactively →