CALML5

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CALML5 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CALML5-associated genes across cancer lineages are MPP and HSC. Each is linked with CALML5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALML5-to-partner and partner-to-CALML5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by CALML5-low versus CALML5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML5→partner) and Y-score (partner→CALML5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMPP →+0.014+1.996.032.01632
SKCMHSC →-0.090-2.290.027.03621
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MPP by CALML5 expression — SKCM

Box plot of MPP in CALML5-low vs CALML5-high samples in SKCM.

Explore this box plot interactively →

Exploration