CALML4

Across TCGA cell cohorts, CALML4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,355 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALML4-associated GO terms across cancer lineages are Brush border assembly, Telomere maintenance via semi-conservative replication, and DNA replication proofreading. Each is linked with CALML4 in more than 19 cancer types. Because this analysis shows association rather than direction, both CALML4-to-partner and partner-to-CALML4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Brush border assembly grouped by CALML4-low versus CALML4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML4→partner) and Y-score (partner→CALML4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Brush border assembly →	+1.591	+1.498	<.001	<.001	3	20
BONE	Telomere maintenance via semi-conservative replication →	+0.177	+1.489	.002	<.001	3	11
BONE	DNA replication proofreading →	+0.177	+1.574	<.001	<.001	3	11
SOFT_TISSUE	Resolution of DNA recombination intermediates →	+0.196	+1.266	<.001	<.001	3	11
BONE	Mycotoxin catabolic process →	-0.177	-1.582	.001	.003	3	10
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.125	+1.487	.006	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,355 associations by consensus.

Brush border assembly by CALML4 expression — OESOPHAGUS

Explore this box plot interactively →