CALML3

Across TCGA patient cohorts, CALML3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,104 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CALML3-associated GO terms across cancer lineages are Skin epidermis development, Prostatic bud formation, and Epidermal cell differentiation. Each is linked with CALML3 in more than 11 cancer types. Because this analysis shows association rather than direction, both CALML3-to-partner and partner-to-CALML3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skin epidermis development grouped by CALML3-low versus CALML3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML3→partner) and Y-score (partner→CALML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Skin epidermis development →	+0.056	+3.536	<.001	<.001	3	12
TGCT	Prostatic bud formation →	+0.125	+1.039	<.001	.003	3	11
ESCA	Epidermal cell differentiation →	+0.070	+4.294	<.001	<.001	3	11
SKCM	Intermediate filament bundle assembly →	+0.246	+2.000	<.001	<.001	3	11
ESCA	Autocrine signaling →	+0.167	+5.472	<.001	<.001	3	11
ESCA	Regulation of integrin biosynthetic process →	+0.132	+3.201	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,104 associations by consensus.

Skin epidermis development by CALML3 expression — ESCA

Explore this box plot interactively →