CALML3

Across TCGA patient cohorts, CALML3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,770 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CALML3-associated genes across cancer lineages are CLCA2, KRT14, and TP53AIP1. Each is linked with CALML3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CALML3-to-partner and partner-to-CALML3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALML3 versus CLCA2 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML3→partner) and Y-score (partner→CALML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CLCA2 →	+2.397	+1.050	<.001	.001	3	4
LSCC	KRT14 →	+2.848	+1.005	<.001	<.001	3	4
LSCC	TP53AIP1 →	+1.182	+0.960	<.001	<.001	3	3
BRCA	KRT17 →	+1.911	+1.049	<.001	<.001	3	3
HNSC	RELCH →	+0.557	+0.755	<.001	<.001	3	3
BRCA	KLF4 →	+1.106	+0.973	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,770 associations by consensus.

CALML3 vs CLCA2 — BRCA

Explore this scatter interactively →