CALML3

Across TCGA cell cohorts, CALML3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,374 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CALML3-associated GO terms across cancer lineages are Cerebral cortex radial glia-guided migration, Telencephalon glial cell migration, and Positive regulation of nucleocytoplasmic transport. Each is linked with CALML3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CALML3-to-partner and partner-to-CALML3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebral cortex radial glia-guided migration grouped by CALML3-low versus CALML3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML3→partner) and Y-score (partner→CALML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cerebral cortex radial glia-guided migration →	+0.192	+0.026	<.001	.004	3	7
BONE	Telencephalon glial cell migration →	+0.192	+0.026	<.001	.004	3	7
LUNG_NSCLC_LUAD	Positive regulation of nucleocytoplasmic transport →	+0.048	+0.061	<.001	.007	3	6
BONE	Cell motility involved in cerebral cortex radial glia guided migration →	+0.151	+0.020	.001	.005	3	6
LUNG_SCLC	Regulation of atrial cardiac muscle cell membrane depolarization →	-1.105	-1.981	<.001	<.001	3	5
LUNG_SCLC	DNA geometric change →	+0.063	+1.529	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,374 associations by consensus.

Cerebral cortex radial glia-guided migration by CALML3 expression — BONE

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