Across TCGA patient cohorts, CALHM6 protein abundance is significantly associated with the protein abundance of many other proteins, with 10,428 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CALHM6-associated proteins across cancer lineages are CSK, FYB1, and BTK. Each is linked with CALHM6 in more than 7 cancer types. Because this analysis shows association rather than direction, both CALHM6-to-partner and partner-to-CALHM6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM6→partner) and Y-score (partner→CALHM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CSK →	+0.550	+0.983	<.001	<.001	3	8
UCEC	FYB1 →	+0.807	+0.953	<.001	<.001	3	8
OV	BTK →	+0.739	+1.071	<.001	<.001	3	7
UCEC	ANKRD44 →	+0.826	+1.490	<.001	<.001	3	7
PDAC	APOL3 →	+0.926	+0.920	.002	.003	2	8
UCEC	ARHGAP30 →	+0.733	+1.086	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,428 associations by consensus.

Exploration

CALHM6 survival (RNA) · tumor vs normal (RNA) · all CALHM6 data types