Across TCGA cell cohorts, CALHM6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CALHM6-associated genes across cancer lineages are OR11H1, TMEM207, and OR4D10. Each is linked with CALHM6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALHM6-to-partner and partner-to-CALHM6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM6→partner) and Y-score (partner→CALHM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR11H1 →	+0.022	+4.371	<.001	.005	3	1
LUNG_NSCLC_LUAD	TMEM207 →	+0.072	+5.472	.003	<.001	3	1
LUNG_NSCLC_LUAD	OR4D10 →	+0.039	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

CALHM6 survival (RNA) · tumor vs normal (RNA) · all CALHM6 data types