CALHM5

Across TCGA patient cohorts, CALHM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,789 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CALHM5-associated proteins across cancer lineages are RARRES2, ISLR, and MSRB3. Each is linked with CALHM5 in more than 9 cancer types. Because this analysis shows association rather than direction, both CALHM5-to-partner and partner-to-CALHM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALHM5 versus RARRES2 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM5→partner) and Y-score (partner→CALHM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RARRES2 →	+0.695	+0.559	<.001	.001	3	10
BRCA	ISLR →	+0.925	+0.806	<.001	<.001	3	10
BRCA	MSRB3 →	+1.076	+0.982	<.001	<.001	3	10
GBM	MYL6 →	+0.446	+0.703	<.001	<.001	3	10
UCEC	MYL9 →	+0.776	+0.456	<.001	<.001	3	10
BRCA	PCOLCE →	+0.878	+0.932	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,789 associations by consensus.

CALHM5 vs RARRES2 — GBM

Explore this scatter interactively →