CALHM5

Across TCGA patient cohorts, CALHM5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,260 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CALHM5-associated genes across cancer lineages are SPARC, COL5A1, and SFRP2. Each is linked with CALHM5 in more than 7 cancer types. Because this analysis shows association rather than direction, both CALHM5-to-partner and partner-to-CALHM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALHM5 versus SPARC in OV, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM5→partner) and Y-score (partner→CALHM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPARC →	+1.828	+1.040	<.001	<.001	3	8
OV	COL5A1 →	+2.110	+0.837	<.001	<.001	3	8
COAD	SFRP2 →	+4.356	+0.582	<.001	<.001	3	8
OV	THY1 →	+1.457	+0.749	<.001	<.001	3	8
OV	COL6A3 →	+1.764	+0.881	<.001	<.001	3	8
OV	FBLN2 →	+1.688	+0.795	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,260 associations by consensus.

CALHM5 vs SPARC — OV

Explore this scatter interactively →