CALHM2

Across TCGA cell cohorts, CALHM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,739 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALHM2-associated GO terms across cancer lineages are Regulation of myoblast fusion, Schwann cell differentiation, and Negative regulation of myoblast fusion. Each is linked with CALHM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CALHM2-to-partner and partner-to-CALHM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CALHM2-low versus CALHM2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM2→partner) and Y-score (partner→CALHM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.106	+1.307	<.001	<.001	3	9
SKIN	Schwann cell differentiation →	+0.079	+1.617	.004	.001	3	8
OVARY	Negative regulation of myoblast fusion →	+0.129	+1.360	<.001	<.001	3	8
OVARY	Regulation of cell cycle G1/S phase transition →	+0.062	+1.324	<.001	.001	3	8
OESOPHAGUS	Negative regulation of G1/S transition of mitotic cell cycle →	+0.077	+1.615	.008	.004	3	8
OESOPHAGUS	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.158	+1.899	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,739 associations by consensus.

Regulation of myoblast fusion by CALHM2 expression — OVARY

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