Across TCGA patient cohorts, CALHM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,072 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible CALHM1-associated GO terms across cancer lineages are Response to UV, Regulation of telomere maintenance via telomere lengthening, and Telomere capping. Each is linked with CALHM1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CALHM1-to-partner and partner-to-CALHM1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM1→partner) and Y-score (partner→CALHM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to UV →	+0.055	+0.109	<.001	.003	2	17
UCS	Regulation of telomere maintenance via telomere lengthening →	+0.040	+0.202	.001	<.001	2	17
STAD	Telomere capping →	+0.041	+0.140	<.001	<.001	3	15
LGG	Dendrite development →	+0.039	+0.792	<.001	<.001	3	15
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.072	+0.150	<.001	<.001	3	15
UCS	RNA-templated DNA biosynthetic process →	+0.046	+0.228	<.001	.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,072 associations by consensus.

Exploration

CALHM1 survival (RNA) · tumor vs normal (RNA) · all CALHM1 data types