Across TCGA cell cohorts, CALHM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,677 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CALHM1-associated GO terms across cancer lineages are Nucleic acid catabolic process, RNA catabolic process, and mRNA cis splicing, via spliceosome. Each is linked with CALHM1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CALHM1-to-partner and partner-to-CALHM1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM1→partner) and Y-score (partner→CALHM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Nucleic acid catabolic process →	+0.052	+0.168	<.001	.001	3	8
SOFT_TISSUE	RNA catabolic process →	+0.059	+0.175	<.001	<.001	3	7
SKIN	mRNA cis splicing, via spliceosome →	+0.065	+0.054	.001	.003	3	7
SOFT_TISSUE	Spliceosomal tri-snRNP complex assembly →	+0.062	+0.077	<.001	.009	3	7
STOMACH	Regulation of protein localization to Cajal body →	+0.092	+0.121	<.001	.003	3	6
STOMACH	Positive regulation of protein localization to Cajal body →	+0.092	+0.121	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,677 associations by consensus.

Exploration

CALHM1 survival (RNA) · tumor vs normal (RNA) · all CALHM1 data types