CALD1

Across TCGA patient cohorts, CALD1 mutation is significantly associated with the RNA expression of many other genes, with 3,161 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CALD1-associated genes across cancer lineages are ABCD1P3, EIF2B2, and TXN2. Each is linked with CALD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CALD1-to-partner and partner-to-CALD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCD1P3 grouped by CALD1-low versus CALD1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALD1→partner) and Y-score (partner→CALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ABCD1P3 →	+0.114	+4.625	<.001	.008	3	3
UCEC	EIF2B2 →	+0.462	+2.032	<.001	<.001	3	3
UCEC	TXN2 →	+0.304	+2.939	<.001	<.001	3	3
UCEC	MINDY4 →	-0.301	-1.509	.005	.004	3	3
UCEC	STAG3L4 →	+0.431	+2.191	<.001	.001	3	3
UCEC	RAD1 →	+0.349	+1.745	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,161 associations by consensus.

ABCD1P3 by CALD1 expression — LUSC

Explore this box plot interactively →