CALD1

Across TCGA patient cohorts, CALD1 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CALD1-associated genes across cancer lineages are ATM, FASN, and Caspase-7-cleavedD198. Each is linked with CALD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CALD1-to-partner and partner-to-CALD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CALD1-low versus CALD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALD1→partner) and Y-score (partner→CALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.503	-1.807	<.001	.025	3	3
COAD	FASN →	+0.532	+2.178	.003	.035	3	2
COAD	Caspase-7-cleavedD198 →	+1.066	+2.178	.004	.035	3	2
UCEC	Rab25 →	-0.290	-2.000	.009	.009	3	2
UCEC	4E-BP1 →	+0.224	+1.515	.013	.033	3	2
UCEC	C-Raf →	+0.122	+1.321	.011	.029	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

ATM by CALD1 expression — UCEC

Explore this box plot interactively →