CALD1

Across TCGA cell cohorts, CALD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,360 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CALD1-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Positive regulation of cytoskeleton organization, and Regulation of protein K48-linked ubiquitination. Each is linked with CALD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CALD1-to-partner and partner-to-CALD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by CALD1-low versus CALD1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALD1→partner) and Y-score (partner→CALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Peptidyl-lysine oxidation →	+1.428	+3.934	<.001	<.001	3	13
BONE	Positive regulation of cytoskeleton organization →	+0.101	+3.323	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of protein K48-linked ubiquitination →	+0.148	+2.872	.003	.004	3	13
LUNG_NSCLC_LUSC	Protein import into peroxisome membrane →	+0.152	+3.441	<.001	.001	3	13
BONE	Positive regulation of cell-substrate adhesion →	+0.143	+2.884	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.098	+2.207	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,360 associations by consensus.

Peptidyl-lysine oxidation by CALD1 expression — BREAST

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