CALD1

Across TCGA cell cohorts, CALD1 mutation is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALD1-associated genes across cancer lineages are PNLIPRP1, EPPIN, and CFC1. Each is linked with CALD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALD1-to-partner and partner-to-CALD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNLIPRP1 grouped by CALD1-low versus CALD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALD1→partner) and Y-score (partner→CALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PNLIPRP1 →	+0.014	+3.362	.008	.007	3	2
BLOOD_Leukemia	EPPIN →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	CFC1 →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	TPPP2 →	+0.041	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCM →	+0.028	+4.922	<.001	.009	3	1
LUNG_NSCLC_LUAD	KCNC2 →	+0.962	+3.215	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

PNLIPRP1 by CALD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →