CALCR

Across TCGA patient cohorts, CALCR protein abundance is significantly associated with the RNA expression of many other genes, with 1,571 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CALCR-associated genes across cancer lineages are SNRPD3, CBX7, and SYNGR1. Each is linked with CALCR in more than 1 cancer types. Because this analysis shows association rather than direction, both CALCR-to-partner and partner-to-CALCR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALCR versus SNRPD3 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCR→partner) and Y-score (partner→CALCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.341	+0.758	.007	.004	3	1
GBM	CBX7 →	+0.395	+0.575	<.001	.004	3	1
GBM	SYNGR1 →	+0.686	+0.709	.003	.008	3	1
GBM	CHADL →	+1.261	+1.089	<.001	<.001	3	1
GBM	ISM2 →	-0.330	-0.919	<.001	<.001	3	1
GBM	RPS6KA5 →	+0.368	+0.971	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,571 associations by consensus.

CALCR vs SNRPD3 — GBM

Explore this scatter interactively →