CALCOCO1

Across TCGA pan-cancer cohorts, CALCOCO1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CALCOCO1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CALCOCO1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CALCOCO1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, LUAD, and GBM are the cancer types where CALCOCO1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.763	0.519	.001	53	view →
LUAD	OS	Tertile	III,IV	0.643	0.996	.018	2	view →
GBM	OS	Median	All	0.262	0.528	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CALCOCO1–HNSC (DFS)

Open the HNSC breakdown →