CALCOCO1

Across TCGA cell cohorts, CALCOCO1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible CALCOCO1-associated genes across cancer lineages are EFCAB3, OR2A2, and TPPP2. Each is linked with CALCOCO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALCOCO1-to-partner and partner-to-CALCOCO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EFCAB3 grouped by CALCOCO1-low versus CALCOCO1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCOCO1→partner) and Y-score (partner→CALCOCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	EFCAB3 →	+0.019	+4.217	<.001	.005	3	1
URINARY_TRACT	OR2A2 →	+0.035	+4.087	<.001	.009	3	1
KIDNEY	TPPP2 →	+0.043	+5.000	<.001	.005	3	1
KIDNEY	DAZ2 →	+0.013	+5.000	<.001	.005	3	1
SKIN	CLEC4C →	+0.054	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

EFCAB3 by CALCOCO1 expression — URINARY_TRACT

Explore this box plot interactively →