CALCB

Across TCGA cell cohorts, CALCB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,838 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CALCB-associated GO terms across cancer lineages are Gamma-aminobutyric acid signaling pathway, Negative regulation of transcription by RNA polymerase I, and Positive regulation of monoatomic ion transport. Each is linked with CALCB in more than 5 cancer types. Because this analysis shows association rather than direction, both CALCB-to-partner and partner-to-CALCB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid signaling pathway grouped by CALCB-low versus CALCB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCB→partner) and Y-score (partner→CALCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Gamma-aminobutyric acid signaling pathway →	-0.200	-0.484	<.001	.008	3	6
BONE	Negative regulation of transcription by RNA polymerase I →	+0.123	+3.203	<.001	<.001	3	6
BONE	Positive regulation of monoatomic ion transport →	-0.142	-2.924	<.001	.004	3	6
BONE	Positive regulation of transcription by RNA polymerase I →	+0.116	+2.463	.006	.001	3	6
OVARY	Negative regulation of chromosome condensation →	+0.099	+0.646	<.001	<.001	3	6
OESOPHAGUS	Calcium ion transport →	-0.051	-0.733	<.001	.009	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,838 associations by consensus.

Gamma-aminobutyric acid signaling pathway by CALCB expression — OVARY

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