CALCB

Across TCGA cell cohorts, CALCB mutation is significantly associated with the mutation status of many other genes, with 608 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CALCB-associated genes across cancer lineages are CHAF1B, OR51B5, and KCNH5. Each is linked with CALCB in more than 1 cancer types. Because this analysis shows association rather than direction, both CALCB-to-partner and partner-to-CALCB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAF1B grouped by CALCB-low versus CALCB-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCB→partner) and Y-score (partner→CALCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CHAF1B →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	OR51B5 →	+3.087	+4.392	.005	.005	1	2
BLOOD_Lymphoma	KCNH5 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	EEF1A1 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	GSX1 →	+6.014	+6.014	.001	.001	1	2
BLOOD_Lymphoma	SLC4A4 →	+4.429	+5.247	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 608 associations by consensus.

CHAF1B by CALCB expression — LARGE_INTESTINE

Explore this box plot interactively →