CALCA

Across TCGA patient cohorts, CALCA RNA expression is significantly associated with the RNA expression of many other genes, with 6,837 significant associations in total. SARC shows the largest number of these associations.

The most reproducible CALCA-associated genes across cancer lineages are CALCB, PDE3B, and UCHL1. Each is linked with CALCA in more than 26 cancer types. Because this analysis shows association rather than direction, both CALCA-to-partner and partner-to-CALCA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALCA versus CALCB in CHOL, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCA→partner) and Y-score (partner→CALCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	CALCB →	+2.120	+3.372	.001	.001	1	27
LAML	PDE3B →	+0.680	+0.179	<.001	<.001	3	12
STAD	UCHL1 →	+1.555	+0.385	<.001	<.001	2	13
PCPG	CGA →	+1.247	+1.574	<.001	<.001	3	12
PAAD	SH3GL2 →	+0.834	+0.335	<.001	.003	3	12
PAAD	SCG3 →	+1.124	+0.333	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,837 associations by consensus.

CALCA vs CALCB — CHOL

Explore this scatter interactively →