CALCA

Across TCGA patient cohorts, CALCA RNA expression is significantly associated with the protein abundance of many other proteins, with 7,074 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CALCA-associated proteins across cancer lineages are BCAR1_S428, CGGBP1, and IRF2BP1. Each is linked with CALCA in more than 3 cancer types. Because this analysis shows association rather than direction, both CALCA-to-partner and partner-to-CALCA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CALCA versus BCAR1_S428 in PDAC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CALCA→partner) and Y-score (partner→CALCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	BCAR1_S428 →	-0.667	-0.271	<.001	<.001	3	3
HNSC	CGGBP1 →	+0.288	+0.335	<.001	.006	3	3
PDAC	IRF2BP1 →	+0.188	+0.319	.001	.001	3	3
LUAD	SPATS2L →	-0.413	-2.382	<.001	<.001	3	3
LSCC	FAM83H →	-0.352	-0.255	.008	<.001	2	4
HNSC	GIPC1 →	-0.549	-0.264	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,074 associations by consensus.

CALCA vs BCAR1_S428 — PDAC

Explore this scatter interactively →