CALB1

Across TCGA pan-cancer cohorts, CALB1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CALB1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CALB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CALB1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where CALB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	III,IV	0.840	0.264	.001	38	view →
CCRCC	OS	Median	All	1.000	0.906	.016	29	view →
LSCC	DFS	Median	All	0.771	0.267	.022	8	view →
UCEC	OS	Tertile	All	0.867	1.000	.025	8	view →
LUAD	DFS	Median	All	0.945	0.428	.003	8	view →
HNSC	DFS	Quartile	IV	0.344	0.865	.035	2	view →
GBM	DFS	Tertile	All	0.785	0.543	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CALB1–PDAC (DFS)

Open the PDAC breakdown →