CAGE1

Across TCGA cell cohorts, CAGE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,338 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAGE1-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Regulation of mRNA processing, and Establishment of RNA localization. Each is linked with CAGE1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CAGE1-to-partner and partner-to-CAGE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by CAGE1-low versus CAGE1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAGE1→partner) and Y-score (partner→CAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.033	+0.052	.003	.008	3	8
STOMACH	Regulation of mRNA processing →	+0.111	+0.071	.002	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.059	+0.147	.007	.003	2	9
LARGE_INTESTINE	RNA localization →	+0.053	+0.044	<.001	.005	3	8
STOMACH	Regulation of transcription initiation by RNA polymerase II →	+0.055	+0.065	<.001	.001	3	7
STOMACH	RNA export from nucleus →	+0.148	+0.075	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,338 associations by consensus.

Establishment of protein localization to organelle by CAGE1 expression — BLOOD_Lymphoma

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