CAGE1

Across TCGA cell cohorts, CAGE1 mutation is significantly associated with the drug of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAGE1-associated genes across cancer lineages are SGC-CBP30, GSK2801, and Mirin. Each is linked with CAGE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAGE1-to-partner and partner-to-CAGE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SGC-CBP30 grouped by CAGE1-low versus CAGE1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAGE1→partner) and Y-score (partner→CAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SGC-CBP30 →	+0.300	+2.649	.034	.046	3	1
LARGE_INTESTINE	GSK2801 →	+0.348	+2.678	.028	.037	2	1
LARGE_INTESTINE	Mirin →	+0.378	+2.646	.046	.047	1	1
LARGE_INTESTINE	5-Fluorouracil →	+0.613	+2.769	.034	.040	1	1
LARGE_INTESTINE	BDILV000379a →	+0.353	+2.649	.021	.046	1	1
LARGE_INTESTINE	IRAK4_4710 →	+0.373	+2.649	.041	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

SGC-CBP30 by CAGE1 expression — LARGE_INTESTINE

Explore this box plot interactively →