CADPS2

Across TCGA pan-cancer cohorts, CADPS2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CADPS2 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CADPS2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CADPS2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, LSCC, and UCEC are the cancer types where CADPS2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.777	0.416	.009	19	view →
LSCC	DFS	Tertile	II,III,IV	0.804	1.000	.007	19	view →
UCEC	DFS	Quartile	All	0.965	0.694	.005	8	view →
PDAC	OS	Quartile	II,III,IV	1.000	0.815	.035	4	view →
HNSC	OS	Tertile	All	0.948	1.000	.043	2	view →
LUAD	OS	Median	III,IV	0.689	0.211	.005	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CADPS2–CCRCC (DFS)

Open the CCRCC breakdown →