CADM4

Across TCGA patient cohorts, CADM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,694 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CADM4-associated proteins across cancer lineages are PAFAH1B3, PRR36, and ARHGAP35. Each is linked with CADM4 in more than 6 cancer types. Because this analysis shows association rather than direction, both CADM4-to-partner and partner-to-CADM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CADM4 versus PAFAH1B3 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CADM4→partner) and Y-score (partner→CADM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAFAH1B3 →	+0.474	+0.839	<.001	<.001	3	7
LSCC	PRR36 →	+0.995	+0.807	.001	<.001	3	6
GBM	ARHGAP35 →	+0.292	+0.616	<.001	<.001	3	6
OV	IRGQ →	+0.380	+0.677	<.001	.009	3	6
HNSC	PSMB10 →	-0.508	-1.112	<.001	<.001	3	5
LSCC	PSMB5 →	+0.478	+0.869	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,694 associations by consensus.

CADM4 vs PAFAH1B3 — OV

Explore this scatter interactively →