CADM3

Across TCGA cell cohorts, CADM3 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CADM3-associated genes across cancer lineages are CCR8, ANO5, and REG1B. Each is linked with CADM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CADM3-to-partner and partner-to-CADM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCR8 grouped by CADM3-low versus CADM3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CADM3→partner) and Y-score (partner→CADM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
LARGE_INTESTINE	ANO5 →	+0.651	+3.453	.001	.009	3	1
LARGE_INTESTINE	REG1B →	+2.047	+3.196	.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.036	+4.415	<.001	<.001	3	1
LUNG_SCLC	APOA4 →	+0.367	+3.898	.005	.005	3	1
LUNG_SCLC	MAGEB4 →	+0.004	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CCR8 by CADM3 expression — SOFT_TISSUE

Explore this box plot interactively →