CADM2-AS2

Across TCGA pan-cancer cohorts, CADM2-AS2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated CADM2-AS2 data layer.

The strongest signal is observed in thymoma (THYM), where higher CADM2-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CADM2-AS2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PRAD show a favorable association.

THYM, THCA, and STAD are the cancer types where CADM2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.169	0.880	<.001	99	view →
THCA	DFS	Tertile	All	0.193	0.839	<.001	99	view →
STAD	DFS	Tertile	IV	0.068	0.480	<.001	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
BLCA	DFS	Tertile	IV	0.138	0.483	.001	27	view →
UCEC	OS	Tertile	III,IV	0.097	0.594	.038	18	view →
SARC	OS	Tertile	All	0.171	0.601	.002	15	view →
LUAD	DFS	Tertile	All	0.680	0.325	.030	12	view →
PRAD	DFS	Tertile	All	0.977	0.759	.042	12	view →
SKCM	DFS	Tertile	All	0.066	0.207	.042	6	view →
KIRP	DFS	Tertile	All	0.702	0.873	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

CADM2-AS2–THYM (OS)

Open the THYM breakdown →