CADM2-AS1

Across TCGA pan-cancer cohorts, CADM2-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CADM2-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher CADM2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CADM2-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and BRCA show a favorable association.

KICH, KIRC, and LUAD are the cancer types where CADM2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
KIRC	DFS	Tertile	III,IV	0.315	0.505	.015	24	view →
LUAD	OS	Tertile	All	0.740	0.828	.017	24	view →
BLCA	OS	Tertile	All	0.364	0.611	.035	18	view →
LGG	OS	Quartile	All	0.938	0.805	<.001	13	view →
UCS	DFS	Tertile	II,III,IV	0.247	0.526	.016	12	view →
BRCA	OS	Median	All	0.944	0.909	.026	10	view →
UVM	DFS	Tertile	III,IV	0.856	0.326	.037	6	view →
THCA	DFS	Tertile	IV	0.493	0.876	.019	6	view →
CESC	OS	Tertile	II,III,IV	0.247	0.618	.030	6	view →
LIHC	OS	Tertile	All	0.243	0.513	.027	6	view →
STAD	DFS	Tertile	All	0.243	0.444	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CADM2-AS1–KICH (DFS)

Open the KICH breakdown →