Across TCGA pan-cancer cohorts, CACYBPP3 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CACYBPP3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CACYBPP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CACYBPP3 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, BRCA, and KIRC are the cancer types where CACYBPP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CACYBPP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.025	.004	7	view →
BRCA	Female	All	+0.099	.007	4	view →
KIRC	All	II,III,IV	−0.016	.014	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: CACYBPP3 RNA expression & survival · all CACYBPP3 data types