CACYBPP2

Across TCGA pan-cancer cohorts, CACYBPP2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CACYBPP2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CACYBPP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CACYBPP2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

MESO, KIRP, and UVM are the cancer types where CACYBPP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	All	0.274	0.450	.002	97	view →
KIRP	DFS	Tertile	All	0.560	0.830	<.001	80	view →
UVM	OS	Median	All	0.423	0.811	<.001	78	view →
LIHC	OS	Tertile	All	0.684	0.838	<.001	46	view →
LUAD	OS	Median	All	0.773	0.848	.003	40	view →
KIRC	DFS	Tertile	II,III,IV	0.777	0.513	.012	33	view →
UCS	OS	Quartile	All	0.416	0.868	.008	26	view →
HNSC	DFS	Median	IV	0.716	0.418	.001	25	view →
LUSC	OS	Quartile	II,III,IV	0.540	0.297	.011	22	view →
SARC	DFS	Median	All	0.491	0.673	.009	18	view →
COAD	OS	Quartile	II,III,IV	0.791	0.536	.004	17	view →
BRCA	OS	Tertile	II,III,IV	0.886	0.948	.006	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CACYBPP2–MESO (DFS)

Open the MESO breakdown →