Across TCGA pan-cancer cohorts, CACYBPP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CACYBPP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CACYBPP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CACYBPP1 is over-expressed in tumor, although a few such as HNSC and LIHC show the opposite, repressed pattern.

HNSC, LIHC, and LUSC are the cancer types where CACYBPP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CACYBPP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	−0.046	.026	2	view →
LIHC	All	II,III,IV	−0.023	.024	2	view →
LUSC	Female	All	−0.099	.023	1	view →
THCA	Female	All	−0.048	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CACYBPP1 RNA expression & survival · all CACYBPP1 data types