CACYBP

Across TCGA pan-cancer cohorts, CACYBP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CACYBP data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CACYBP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CACYBP expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where CACYBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.756	0.928	.004	23	view →
LUAD	DFS	Tertile	All	0.490	0.922	.009	9	view →
LSCC	OS	Median	III,IV	0.451	0.840	.015	4	view →
PDAC	DFS	Tertile	IV	0.741	0.205	.024	3	view →
HNSC	DFS	Median	III,IV	0.708	0.859	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CACYBP–CCRCC (OS)

Open the CCRCC breakdown →