CACYBP

Across TCGA patient cohorts, CACYBP protein abundance is significantly associated with the RNA expression of many other genes, with 19,204 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CACYBP-associated genes across cancer lineages are NEK2, NUF2, and PFDN2. Each is linked with CACYBP in more than 9 cancer types. Because this analysis shows association rather than direction, both CACYBP-to-partner and partner-to-CACYBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACYBP versus NEK2 in BRCA, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACYBP→partner) and Y-score (partner→CACYBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NEK2 →	+1.148	+0.422	<.001	<.001	3	10
BRCA	NUF2 →	+1.367	+0.481	<.001	<.001	3	10
UCEC	PFDN2 →	+0.953	+0.246	<.001	<.001	3	10
BRCA	UCHL5 →	+0.698	+0.402	<.001	<.001	3	9
COAD	CENPL →	+0.683	+0.468	<.001	<.001	3	9
OV	SGO1 →	+0.769	+0.410	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,204 associations by consensus.

CACYBP vs NEK2 — BRCA

Explore this scatter interactively →