CACYBP

Across TCGA patient cohorts, CACYBP mutation is significantly associated with the RNA expression of many other genes, with 510 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACYBP-associated genes across cancer lineages are RNA5SP423, SNORD115-39, and MIR6134. Each is linked with CACYBP in more than 1 cancer types. Because this analysis shows association rather than direction, both CACYBP-to-partner and partner-to-CACYBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP423 grouped by CACYBP-low versus CACYBP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACYBP→partner) and Y-score (partner→CACYBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP423 →	+0.880	+2.302	<.001	.005	3	2
BRCA	SNORD115-39 →	+0.380	+7.731	<.001	.009	3	2
BRCA	MIR6134 →	+0.304	+9.057	<.001	.003	3	1
BRCA	MIR6507 →	+0.700	+8.055	<.001	.007	3	1
BRCA	MIR7151 →	+0.482	+8.471	<.001	.005	3	1
UCEC	TAF9 →	+0.595	+3.191	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 510 associations by consensus.

RNA5SP423 by CACYBP expression — UCEC

Explore this box plot interactively →