CACUL1

Across TCGA patient cohorts, CACUL1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,349 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CACUL1-associated genes across cancer lineages are ABRAXAS2, GLRX3, and EXOSC1. Each is linked with CACUL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CACUL1-to-partner and partner-to-CACUL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACUL1 versus ABRAXAS2 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACUL1→partner) and Y-score (partner→CACUL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABRAXAS2 →	+0.439	+0.221	<.001	<.001	3	7
HNSC	GLRX3 →	+0.556	+0.276	<.001	<.001	2	7
OV	EXOSC1 →	+0.347	+0.257	.003	<.001	2	7
UCEC	BCCIP →	+0.495	+0.226	.001	.002	2	6
OV	DENND10 →	+0.541	+0.323	<.001	<.001	3	5
UCEC	ACTR1A →	+0.560	+0.202	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,349 associations by consensus.

CACUL1 vs ABRAXAS2 — LSCC

Explore this scatter interactively →