CACUL1

Across TCGA cell cohorts, CACUL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,486 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CACUL1-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Endosomal transport, and Macroautophagy. Each is linked with CACUL1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CACUL1-to-partner and partner-to-CACUL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by CACUL1-low versus CACUL1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACUL1→partner) and Y-score (partner→CACUL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Viral translational termination-reinitiation →	+0.106	+0.942	<.001	<.001	3	17
BONE	Endosomal transport →	+0.062	+0.671	.001	<.001	3	16
STOMACH	Macroautophagy →	+0.062	+0.740	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Protein deubiquitination →	+0.058	+0.852	.002	.001	3	15
STOMACH	Retrograde transport, endosome to Golgi →	+0.068	+0.965	.002	.001	3	15
STOMACH	Phosphatidylinositol metabolic process →	+0.058	+1.337	.003	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,486 associations by consensus.

Viral translational termination-reinitiation by CACUL1 expression — BLOOD_Lymphoma

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