Across TCGA patient cohorts, CACTIN-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,163 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CACTIN-AS1-associated GO terms across cancer lineages are Nucleotide-excision repair, Protein localization to microtubule organizing center, and Positive regulation of DNA repair. Each is linked with CACTIN-AS1 in more than 30 cancer types. Because this analysis shows association rather than direction, both CACTIN-AS1-to-partner and partner-to-CACTIN-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACTIN-AS1→partner) and Y-score (partner→CACTIN-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nucleotide-excision repair →	+0.054	+0.469	<.001	<.001	3	31
ESCA	Protein localization to microtubule organizing center →	+0.083	+0.273	<.001	<.001	3	31
DLBC	Positive regulation of DNA repair →	+0.041	+0.431	.002	<.001	3	30
ESCA	Positive regulation of canonical Wnt signaling pathway →	+0.061	+0.266	<.001	<.001	3	30
DLBC	Positive regulation of double-strand break repair via homologous recombination →	+0.067	+0.428	<.001	<.001	3	30
DLBC	Regulation of mRNA export from nucleus →	+0.095	+0.471	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,163 associations by consensus.

Exploration

CACTIN-AS1 survival (RNA) · tumor vs normal (RNA) · all CACTIN-AS1 data types