CACNG8

Across TCGA pan-cancer cohorts, CACNG8 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CACNG8 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CACNG8 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CACNG8 expression acts as an unfavorable survival marker.

LUAD and BLCA are the cancer types where CACNG8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.057	0.788	<.001	30	view →
BLCA	DFS	Median	III,IV	0.158	0.550	.003	21	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CACNG8–LUAD (OS)

Open the LUAD breakdown →