CACNG8

Across TCGA patient cohorts, CACNG8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,302 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNG8-associated genes across cancer lineages are SOX10, SLC16A8, and SUN2. Each is linked with CACNG8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNG8-to-partner and partner-to-CACNG8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNG8 versus SOX10 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG8→partner) and Y-score (partner→CACNG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOX10 →	+1.171	+0.528	<.001	<.001	3	1
GBM	SLC16A8 →	+0.428	+0.445	<.001	<.001	3	1
GBM	SUN2 →	+0.454	+0.489	<.001	<.001	3	1
GBM	RASL10A →	+1.027	+0.706	<.001	<.001	3	1
GBM	NEFH →	+1.024	+0.573	<.001	<.001	3	1
GBM	RASD2 →	+0.697	+0.718	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,302 associations by consensus.

CACNG8 vs SOX10 — GBM

Explore this scatter interactively →