CACNG8

Across TCGA cell cohorts, CACNG8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,103 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CACNG8-associated GO terms across cancer lineages are Regulation of telomere capping, IMP salvage, and Positive regulation of mismatch repair. Each is linked with CACNG8 in more than 8 cancer types. Because this analysis shows association rather than direction, both CACNG8-to-partner and partner-to-CACNG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere capping grouped by CACNG8-low versus CACNG8-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG8→partner) and Y-score (partner→CACNG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of telomere capping →	+0.093	+0.668	<.001	.005	3	9
LUNG_NSCLC_LUSC	IMP salvage →	+0.205	+0.889	<.001	.001	3	7
STOMACH	Positive regulation of mismatch repair →	-0.174	-1.515	<.001	<.001	3	7
LIVER	Regulation of glutamate uptake involved in transmission of nerve impulse →	+0.234	+1.026	.008	.004	2	8
CNS	Chaperone-mediated autophagy →	+0.087	+0.716	<.001	.002	3	6
CNS	Regulation of protein K48-linked ubiquitination →	+0.098	+0.851	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,103 associations by consensus.

Regulation of telomere capping by CACNG8 expression — OESOPHAGUS

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