CACNG8

Across TCGA cell cohorts, CACNG8 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CACNG8-associated genes across cancer lineages are USP17L3, RBMY1A1, and OR10Q1. Each is linked with CACNG8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNG8-to-partner and partner-to-CACNG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L3 grouped by CACNG8-low versus CACNG8-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG8→partner) and Y-score (partner→CACNG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	USP17L3 →	+0.012	+4.922	.009	.009	3	2
OVARY	RBMY1A1 →	+0.143	+5.807	<.001	.001	3	1
LARGE_INTESTINE	OR10Q1 →	+0.125	+3.920	<.001	.005	3	1
LUNG_NSCLC_LUAD	IQCF6 →	+0.081	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	MT1HL1 →	+0.130	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

USP17L3 by CACNG8 expression — BLOOD_Leukemia

Explore this box plot interactively →