CACNG7

Across TCGA patient cohorts, CACNG7 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNG7-associated genes across cancer lineages are YAP_pS127, PI3K-p110-a, and Cyclin-B1. Each is linked with CACNG7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CACNG7-to-partner and partner-to-CACNG7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YAP_pS127 grouped by CACNG7-low versus CACNG7-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG7→partner) and Y-score (partner→CACNG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	YAP_pS127 →	-0.417	-3.000	.012	.036	3	3
SKCM	PI3K-p110-a →	+0.158	+2.321	.039	.035	3	3
UCEC	Cyclin-B1 →	+0.601	+3.321	.007	.010	3	2
UCEC	TIGAR →	+0.131	+1.933	.032	.009	3	2
STAD	Akt_pT308 →	-0.318	-3.000	.027	.036	3	1
STAD	Claudin-7 →	+0.903	+3.000	.007	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

YAP_pS127 by CACNG7 expression — STAD

Explore this box plot interactively →