CACNG6

Across TCGA patient cohorts, CACNG6 mutation is significantly associated with the RNA expression of many other genes, with 394 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNG6-associated genes across cancer lineages are MIR138-1, ATP13A5-AS1, and IGHD2-15. Each is linked with CACNG6 in more than 2 cancer types. Because this analysis shows association rather than direction, both CACNG6-to-partner and partner-to-CACNG6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR138-1 grouped by CACNG6-low versus CACNG6-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG6→partner) and Y-score (partner→CACNG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR138-1 →	+0.356	+2.445	<.001	.002	3	3
COAD	ATP13A5-AS1 →	+0.279	+5.602	<.001	.004	3	2
HNSC	IGHD2-15 →	+1.057	+3.904	.008	.007	3	2
HNSC	MIR1285-2 →	+0.277	+4.526	<.001	.007	3	2
UCEC	HSBP1P2 →	+0.593	+3.541	.004	.007	3	2
LUSC	MIR875 →	+0.469	+4.151	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 394 associations by consensus.

MIR138-1 by CACNG6 expression — LUAD

Explore this box plot interactively →